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Considering that NF-B activity is directly linked to the LPS-induced expression of iNOS and secretion of NO, it can be concluded that AM404 most likely modulates the secretion of NO from LPS-stimulated microglia through its inhibitory action on the NF-B pathway [70,71]

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Logsdon GA, Vollger MR, Eichler EE

Oral ginseng formula combined with pharmacotherapy improved respiratory symptoms and quality of life, and reduced exacerbation of COPD compared to placebo, non-ginseng formula, or pharmacotherapy alone (An 2011)

Mas-Bargues C, Borras C, Vina J (2021) Bcl-xL as a modulator of senescence and aging